Cosmedix Elite Pepoxide Antioxidant Peptide Concentrate 30ml
Description
Description
Concentrated antioxidant serum with 16 actives from the Elite line
The Cosmedix Elite line forms a separate product category within the Cosmedix range, specially formulated for the skin before and after advanced dermatological treatments such as chemical peels, ablative laser therapy, and microneedling. These formulas are used in dermatological clinics and by medically trained aestheticians to shorten recovery time, minimize post-procedure redness, and maximize treatment results. Pepoxide is the antioxidant flagship of this Elite line — a concentrated antioxidant serum that surpasses the standard Cosmedix offering.
Pepoxide combines sixteen chiral correct antioxidants with growth factors, peptides, and pigment regulators in one concentrated formula. Astaxanthine, superoxide dismutase, and Spin Trap form the core; fifteen additional ingredients — including resveratrol, L-glutathione, ferulic acid, and quercetin — enhance oxidative protection. Acetyl hexapeptide-1 conditions the skin and improves the visibility of fine lines and wrinkles. A professional level of anti-aging rarely combined in one formula, with a chiral correct composition that the skin recognizes more efficiently than classic mirror forms.
Benefits
- Protects the skin with sixteen chiral correct antioxidants
- Reduces the visibility of fine lines and wrinkles with peptides
- Reduces post-procedure redness in advanced treatments
- Regulates melanocytes for a more even skin tone
- Contains growth factors that support cellular renewal
- Gluten-free — also for Dermatitis Herpetiformis
Active ingredients
Astaxanthine: A red carotenoid from microalgae that is among the most powerful antioxidants in nature — research indicates it is up to 6000 times stronger than vitamin C on specific oxidative pathways. Works on both aqueous and fatty parts of the cell, making it active in all skin layers.
Spin Trap (Phenyl T-Butylnitrone): A high-quality antioxidant with selective action — captures harmful free radicals (Reactive Oxygen Species) without affecting healthy oxygen molecules. An 'intelligent' antioxidant used in the Elite line for targeted maximum precision.
L-Superoxide Dismutase (SOD): A natural enzyme that is among the most powerful antioxidants in the body. Neutralizes the harmful superoxide radical before it can react with skin cells — a first line of defense against oxidative damage.
L-Glutathione: The "mother of all antioxidants" according to many skin scientists. Plays a central role in the skin's natural detox system and also affects pigment regulation through melanocyte modulation.
Resveratrol (Polygonum Cuspidatum): The famous antioxidant from red wine research. Protects the skin against photoaging and helps support skin structure at the cellular level. Combined with other antioxidants in Pepoxide for synergistic action.
Acetyl Hexapeptide-1: A peptide with proven firming effects. Deeply conditions the skin and contributes to visible reduction of fine lines and wrinkles. Works through a different mechanism than retinol, allowing complementary use without overload.
Ferulic acid: An antioxidant that enhances the effect of vitamin C and protects the skin from UV-induced damage. In Pepoxide, it works synergistically with the broader antioxidant complex.
Quercetin: A polyphenol antioxidant from plant sources with demonstrated anti-inflammatory effects. Particularly valuable in a formula aimed at reducing post-procedure redness.
Totarol: A lesser-known natural antioxidant from the totara tree. Proven antibacterial and skin-soothing effects make the Pepoxide formula especially suitable for post-procedure skin.
Caffeine: Acts as a microcirculation stimulant and helps reduce the visibility of dark circles and fatigue markers in the skin.
Milk thistle extract (Silybum Marianum): A traditional herbal extract with powerful hepatoprotective effects — also providing antioxidant benefits to the skin. Known in naturopathy for its protective properties.
Rhodiola Rosea root extract: An adaptogenic root that helps the skin cope with stressors — both internal (psychological stress) and external (UV, pollution). An ingredient that structurally supports resilience.
Waltheria Indica leaf extract: A plant extract with clinically studied effects on tyrosinase — the enzyme responsible for pigment formation. Specifically targets melanocytes and contributes to a more even skin tone.
Cypress oil (Cupressus Sempervirens): An essential oil with antioxidant and skin-soothing properties, traditionally used for sensitive and irritated skin.
Grapefruit peel oil and hydrolyzed collagen: Additional ingredients that nourish, soothe the skin, and contribute to the serum's sensory experience.
Cocos Nucifera (coconut) sap and Mannitol: Nourishing, hydrating ingredients that make the formula comfortable for daily use, even on sensitive skin.
How to use
- Cleanse the skin in the morning and/or evening with a Cosmedix Elite cleanser (Rx Clean or Gentle Clean) or another suitable Cosmedix cleanser
- Tone the skin with a suitable toner according to your routine
- Dispense one to two pumps of Pepoxide into the palm of your hand
- Gently spread over face, neck, and décolleté with upward movements
- Allow to absorb for a few minutes before applying a moisturizer
- In the morning: Follow with a day cream and always an SPF
- In the evening: Follow with a night cream of your choice
- Suitable for both morning and evening use — Cosmedix Elite recommends both for maximum antioxidant protection
- For planned ablative treatment: Start daily Pepoxide two weeks before the treatment for optimal skin preparation
Suitable for
- Preparation for or recovery from ablative laser, chemical peel, or dermatological treatments
- Mature skin with visible signs of aging
- Menopausal and perimenopausal skin
- Skin exposed to intense environmental damage (strong UV, pollution)
- For those seeking maximum anti-aging effect at a chirally correct level
- Gluten-free routine — also for Dermatitis Herpetiformis
Frequently asked questions
What is the difference between the Cosmedix Elite line and the regular Cosmedix range?
Cosmedix Elite is a professional sub-line specifically developed for use in combination with dermatological treatments. Unlike the regular Cosmedix line focused on daily anti-aging and skincare, Elite focuses on optimizing post-procedure recovery and maximizing treatment results. The Elite formulas are therefore often sold in dermatology clinics and medical spas. Pepoxide is Elite’s antioxidant flagship and can also be used outside a professional treatment context as a concentrated anti-aging serum.
What does 'chirally correct' mean and why is it important?
Many cosmetic ingredients exist in two mirror-image forms — L-form and D-form — both created in a lab but recognized differently by the body. Chirally correct ingredients use only the L-form (the natural variant produced by the body itself). The result: more efficient action at lower concentrations and significantly less chance of irritation or side effects. Pepoxide uses chirally correct versions of its 16 antioxidants, making the serum more effective than most classic antioxidant formulas.
When will I see the first results from Pepoxide?
The moisturizing and calming effects are noticeable within a few days — the skin feels more balanced. For structural improvement of fine lines, skin tone, and firmness, daily use for eight to twelve weeks is recommended. When used before a planned ablative treatment: start two weeks earlier for optimal skin preparation — Cosmedix Elite strongly recommends this for maximum treatment results.
Can I combine Pepoxide with other active ingredients like retinol or vitamin C?
Yes. Pepoxide works on the antioxidant pathway, not just on exfoliation or pigment regulation, making it excellent to combine with other actives. Classic routine: Pepoxide in the morning followed by SPF, retinol product like Define or Refine in the evening. The antioxidants in Pepoxide also protect the stability of vitamin C products in the same routine and reduce possible retinol sensitivity.
Is Pepoxide suitable for sensitive skin?
Yes, and it is strongly recommended for sensitive skin types. The chirally correct composition, the calming effects of Rhodiola, totarol, and quercetin, and the absence of retinoids or harsh acids make Pepoxide particularly tolerable. For rosacea or very reactive skin, it can even be a valuable addition to soothe redness and protect against oxidative triggers.
Can I use Pepoxide during pregnancy or breastfeeding?
Yes. The formula contains no retinoids, salicylic acid, or other ingredients that are discouraged during these periods. The antioxidant and peptide components are generally considered safe for use during pregnancy and breastfeeding. For maximum certainty, always consult your midwife if in doubt.
What is the difference between Pepoxide and Affirm Antioxidant Firming Serum?
Both are antioxidant serums with overlap in some ingredients (Spin Trap, resveratrol, SOD, glutathione). Affirm contains ten actives and is aimed at preventive anti-aging — suitable for the regular Cosmedix routine. Pepoxide contains sixteen chirally correct antioxidants plus peptides, growth factors, and pigment regulators — a professional level originally developed for post-procedure recovery. For those seeking maximum anti-aging effect or preparing for a dermatological treatment, Pepoxide is the targeted choice; for daily maintenance, Affirm is sufficient.
How long does a 30ml bottle last?
With daily use twice a day, a bottle usually lasts two to three months. With once a day use, this comes to four to five months. The pump bottle doses precisely and keeps the serum fresh until the last drop — important for a formula with sixteen active antioxidants whose stability would decrease faster without pump packaging.

