Schrammek Time Control RetiNight Essence 30ml
Description
Description
Clinically tested anti-aging night essence with Vitanol BIO
Some skincare products stand out not because of marketing, but because of scientific data. The RetiNight Essence is the top serum within the Dr Schrammek line — and the only product with clinical study results from a German university institute according to international GCP guidelines. With regular use, wrinkle depth decreases by 26%, wrinkle volume by 11%, and skin elasticity improves by 18%.
What makes this serum unique is the combination of a mild form of vitamin A with Vitanol® BIO, a plant-based ingredient that has the same cell-renewing effect as retinol but without the known side effects. Supplemented with the peptide complex Matrixyl 3000 and the patented Aquaxyl for deep hydration, this night essence works on multiple levels simultaneously while you sleep. Upon waking, the skin feels and looks fresher, smoother, and visibly younger.
Benefits
- Clinically proven: 26% less wrinkle depth and 18% more elasticity
- Stimulates cell renewal with the combination of vitamin A and plant-based Vitanol BIO
- Builds collagen through Matrixyl 3000 and Palmitoyl Proline peptides
- Hydrates deeper and restructures the skin with Aquaxyl
- Suitable for sensitive mature skin that cannot tolerate pure retinol
Active ingredients
Vitanol® BIO (Medicago Sativa / Alfalfa extract): An innovative plant-based ingredient with a retinol-like effect, derived from alfalfa. Activates the same skin-renewing processes as classic vitamin A — cell division, collagen stimulation, and skin renewal — but without the known irritation, flaking, or light sensitivity. Therefore excellent for people who cannot tolerate retinol or react sensitively to it.
Retinyl Palmitate (Vitamin A Palmitate): A milder ester form of retinol that is gradually converted into active vitamin A in the skin. This phased activation delivers the skin-renewing benefits of retinol in a gradual, comfortable way. Combined with Vitanol® BIO, a synergistic effect arises that shows measurable results in clinical tests.
Matrixyl® 3000 (Palmitoyl Tetrapeptide-7 & Tripeptide-1): A patented peptide complex that stimulates skin cells to produce more collagen, elastin, and hyaluronic acid. Works on a deeper level than superficial care and renews the extracellular matrix — the connective tissue network that gives the skin its firmness and resilience.
Palmitoyl Proline: An additional peptide that specifically promotes connective tissue production and works together with Matrixyl 3000. Strengthens the skin structure at the cellular level and contributes to the measured 18% improvement in elasticity in the clinical study.
Aquaxyl™ (Xylitylglucoside + Xylitol complex): A patented hydrating ingredient that restructures the skin’s natural moisture balance. Works differently than classic hyaluronic acid — Aquaxyl promotes the natural production of moisture-binding substances within the skin itself, for long-lasting hydration from within. Also strengthens the skin barrier.
Nourishing oil blend (Olive, Sesame, Camellia, Cranberry & Evening Primrose): Five carefully selected plant oils that enhance each other’s effects. Olive oil provides oleic acid, sesame oil soothes, camellia seed oil is rich in antioxidants, cranberry oil supplies essential omega fatty acids, and evening primrose oil contains gamma-linolenic acid — all crucial for restoring a mature skin barrier.
Rosemary extract & Vitamin E (Tocopherol): Two powerful antioxidants that reinforce each other. Protect the skin against oxidative stress and keep the active ingredients stable in the skin, allowing them to work longer during the night.
How to use
- Thoroughly cleanse your face in the evening to remove makeup and daytime impurities
- Optionally apply a toner to prepare the skin
- Press a few drops of RetiNight Essence into your palm and spread over face, neck, and décolleté
- Gently pat the essence in and allow it to absorb for a few moments
- Follow with the Time Control Night Cream for maximum effect and protection
- Always use sun protection in the morning, even though this is a night product
Suitable for
- Mature, demanding skin from around 40 years with deeper lines
- Skin that cannot tolerate pure retinol — Vitanol BIO is a mild alternative
- Dull complexion that has lost its natural glow
- Skin with loss of resilience and firmness
- People who appreciate scientifically supported anti-aging
- Vegan-conscious users (the formula is completely vegan)
Frequently asked questions
What are the exact results from the clinical study?
In an independent clinical study according to GCP guidelines, conducted at a German university institute, the following results were measured after regular use: wrinkle depth decreased by 26%, wrinkle volume decreased by 11%, and skin elasticity improved by 18%. The full study is publicly available via the official Dr Schrammek website. It is one of the few Dr Schrammek products with this standardized clinical evidence.
What is the difference between Vitanol BIO and regular retinol?
Classic retinol can cause irritation, dryness, flaking, and light sensitivity — side effects that cause many people to stop using retinol. Vitanol BIO is a plant extract from alfalfa that activates the same cell-renewing processes as retinol but without these side effects. In the RetiNight Essence, it is combined with a mild retinol form for a dual mechanism of action.
Do I still need to use a night cream after this essence?
Yes, the RetiNight Essence is a concentrated essence that works deeper in the skin and has little occlusive effect itself. The Time Control Night Cream locks in the active ingredients and ensures they can work overnight instead of evaporating. Additionally, the Night Cream adds nourishing oils that are important on their own for mature skin. The combination of both products delivers the full results as measured in the clinical study.
Can I use this product if I have never used retinol before?
Yes, this serum is especially attractive for retinol beginners because the combination of Vitanol BIO and mild Retinyl Palmitate is much better tolerated than classic retinol. Start by using it every other evening for the first two weeks to allow the skin to adjust, then build up to daily use. If slight dryness occurs: combine with an extra nourishing night cream.
Can I combine this serum with other actives like vitamin C or acids?
Vitamin C can be used in the morning, RetiNight in the evening — an ideal combination. With chemical acids (AHA, BHA), caution is advised: do not use them on the same evening as RetiNight to avoid overloading the skin barrier. For example, alternate: three evenings of RetiNight, two evenings of acids, and the remaining evenings only a hydrating care. The Time Control Night Cream can always be used on top of RetiNight.
How long does it take to see results?
The first effects — smoother skin texture and a rested, fresh appearance in the morning — are often visible after just a few days of use. The measured clinical results of 26% less wrinkle depth are expected after at least eight to twelve weeks of daily use. With longer use, the effect is cumulative: the longer you faithfully use the serum, the clearer and more lasting the results.

